KnowBe4, a global leader in cybersecurity awareness and training, has unveiled breakthrough innovations that train both humans and AI agents to defend against evolving cyber threats. Through its HRM+ platform, KnowBe4 aims to address the most critical aspects of security — human and AI agent risk management.

According to Gartner, forty percent of enterprise applications will be integrated with task-specific AI agents by 2026, up from less than 5% today. As these AI agents become increasingly vital to operations, they also emerge as new targets for theft, adversarial manipulation, and misuse — emphasizing the growing importance of employee AI literacy.

Reports such as the 2025 Verizon Data Breach Investigations Report confirm that the human element contributes to over 60% of breaches, with social engineering remaining a leading attack vector. Recognizing this, KnowBe4 is advancing smarter defenses that address the dynamic between humans and AI agents to strengthen overall cybersecurity strategies.

“We are delivering adaptive, personalized, AI-driven defenses today to safeguard the next-generation global workforce,” said Bryan Palma, CEO of KnowBe4. “We both guard humans against AI-driven attacks and shield AI systems from exploitation. KnowBe4 is uniquely positioned to protect enterprise AI agents by securing the essential human-agent interaction layer. As AI becomes both a powerful tool and a potential target, safeguarding this interaction point is crucial.”

As cyber threats become increasingly sophisticated through AI, KnowBe4’s HRM+ platform takes a defense-in-depth approach that extends protection beyond the gateway layer. Built on 15 years of user behavior and threat intelligence data, HRM+ delivers comprehensive security that covers every interaction layer — from productivity tools and human users to AI agents themselves.

This multi-layered defense includes:

  • Agent-Safe Behavior Training: Just as employees learned to identify malicious links, they now learn to safely interact with and oversee AI agents.
  • Prompt Injection & Manipulation Defense: Simulated attacks train global teams to recognize and resist adversarial inputs designed to hijack enterprise AI systems.
  • Risk Scoring for Agent Interactions: Expanding KnowBe4’s industry-leading risk scoring to measure susceptibility to AI agent misuse for comprehensive risk quantification.

A KnowBe4 customer highlighted the company’s agility in addressing emerging threats: “Threats evolve constantly. KnowBe4 adapts their training to match the current landscape. AI Defense Agents, in particular, help organizations stay ahead of evolving risks.”

KnowBe4 continues to pioneer advancements in AI-driven human risk management. Explore previous releases and view the demo presented at the KB4-CON Conference 2025 to learn more about its latest capabilities.

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